Comprehensive Prostate
Cancer Treatment Information
Some
100,000 men each year are diagnosed with Prostate cancer while
approximately 30,000 men die from the disease each year. Prostate
cancer is the most common cancer found in men and is second
only to lung cancer when related to deaths. Almost 80 percent of men who are diagnosed with prostate cancer are
over the age of 65. However,
there is a small incidence of the disease in men in there thirties.
Studies
have shown that advancing age, race, hormonal influences, and
environment all play a role in its development. There is also
a strong family history variable, individuals who have a immediate
family member with Prostatic cancer are two times as likely to
develop the disease. If two family members are affected then the
risk of a third member of the family can be as high as five times
that of the general population.
The
Prostate is a small walnut size gland that surrounds the urethra
near the base of the bladder. Normal ejaculation produces about
3cc of semen. The sperm makes up less than one percent of the volume, with the
seminal vesicles and the prostate producing about ninety-five
percent of the total volume.
Symptoms of Prostate Cancer
Many men as they get older will
develop benign prostate hyperplasia. This is a non- cancerous
enlargement of the prostate gland.
As the gland enlarges it can impede the flow of urine
causing symptoms that are very similar to those found in
individuals with prostate cancer.
Therefore
men who experience any of the following symptoms should seek
immediate medical advice:
-
Difficulty in urinating resulting in increase in
frequency and/or interrupted flow of urine.
-
Pain or a burning sensation when urinating.
-
Pain in the lower back, upper thighs or pelvis
region.
Many
times the above symptoms will not be present until the prostate
cancer is in the advance stages. Therefore all men over the age
of forty should have a complete physical including a rectal exam.
The rectal exam can readily detect an enlarged prostate
and in some cases prostate cancer.
If
your physician suspects you are at risk he/she may order some
diagnostic tests. The tests may include a Prostate Specific Antigen,
which detects an abnormal substance released by cancer cells.
Transrectal ultrasound is another diagnostic test that uses a
probe that is inserted into the rectum and can identify identify
abnormalities within the prostate.
Theses
initial test may warrant a biopsy of the tissue. The physician
will then obtain a biopsy of the tissue by inserting a small needle
through the rectum to remove some prostate cells. A pathologist
who grades the cancer subsequently examines these cells.
The grade of the cancer can determine the method of treatment.
Generally, a lower grade tumor is easily managed as compared to
a high-grade tumor that is more aggressive and likely to spread
to other regions. The Gleason system provides a good correlation
between the histologic appearance of a carcinoma and the clinical
stage (how far the tumor as spread) and the prognosis of the neoplasm.
Prostate Cancer Treatment
Options
Depending
on the diagnosis your physician will determine your treatment
options. Radiation and surgery are generally used when the cancer
is confined to the prostate, while hormonal treatment is used
when the cancer has spread to other regions.
Radiation
Therapy - this form
of treatment is usually indicated when the cancer is confined
to the prostate or if the cancer as spread to other regions but
surgery is not an option. Radiation therapy is usually performed
on an outpatient basis and involves high doses of radiation directed
at the prostate. Treatment may last for several weeks depending
on the grade and/or the size of the tumor. Side effects include
burning while urinating, headaches, nausea and vomiting, etc.
Surgery - involves the excision of the prostate gland by an
urologist. The procedure
involves
excising the prostate while avoiding the surrounding urethra and
nerves. Side effects from surgery can include incontinence and/or
impotence.
Hormonal - treatment is generally used when the prostate cancer
has spread to other regions of the body and/or when surgery is
not an option. Hormonal therapy works by depriving the tumor cells
of testosterone a hormone that promotes growth of the malignant
cells. By limiting the amount of Testosterone the tumor will generally
reduce in size. Hormonal therapy can be provided by surgical excision
of the testes or by taking prescription medications such LH-HR
analogs, which prevent the body from producing Testosterone. Side
effects of the LH-HR analogs include impotence and possibly hot
flashes.
The
prognosis of individuals with prostate cancer is primarily related
to the stage of the disease. Localized disease treated with surgery
and/or radiotherapy can expect a 10-year survival rate of 50 to
80%. Individuals with advanced disease treated with orchiectomy,
or the administration of LH-HR analogs can expect 10-year survival
rates 10-40%.
Although
treatment methods have improved in recent years early detection
is still the mainstay to treating the disease. Males over the
age of 40 years of age should have a complete physical exam on
a yearly basis.